EU emissions trading: navigating between Scylla and Charybdis

The cirrhotic hepatocyte: navigating between Scylla and Charybdis.

In the chronically injured and cholestatic liver, the various hepatic cell types are exposed to a vicious cocktail of toxic and potentially lethal ingredients, such as cytokines, reactive oxygen species (ROS), bile acids, endotoxin and Fas-Ligand expressed on immune cells. Some liver cells thrive in this hostile environment, e.g. stellate cells, which start to proliferate and produce excessive ...

Between Scylla and Charybdis.

The ethical dilemmas of treating fulminant (or subfulminant) hepatic failure with liver replacement have been apparent since the earliest trials of this procedure. Acute hepatic failure was the indication for orthotopic liver transplantation in only I of our first 237 recipients I and accounted for only 8 of the next 300.2 Our reluctance to proceed with more cases was that unlike candidates who...

Psychiatric paternalism between Scylla and Charybdis

As much as strong medical paternalism should never be exercised, some weak paternalism towards patients is, on the contrary, part of physicians' and society's moral obligation. So far, this is a widely consented position in medical ethics. What then are the defining and the justifying conditions for legitimate weak paternalism in psychiatry? In this presentation it is argued in favor of three n...

Delphi: Somewhere between Scylla and Charybdis?

N-acetylcysteine somewhere between Scylla and Charybdis.

hiele et al. (1) report a study dealing with the impact of -acetylcysteine (NAC) administered simultaneously on preventng iodinated contrast agent-induced nephropathy and reperfusion njury in patients with ST-segment elevation myocardial infarction reated by percutaneous coronary intervention (PCI). The study ncluded 126 patients compared with a placebo-treated group. heir results as well as co...